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Keywords:

  • catanionic surfactants;
  • drug delivery;
  • promethazine;
  • self-assembly;
  • vesicles
Thumbnail image of graphical abstract

Skin deep: A bioactive formulation for dermal delivery of antihistamines is obtained by using the original properties of catanionic associations towards self-assembly in water. The drug, which participates in its own transport, is preserved from photodegradation when solubilised in the bioactive formulation. The drug release through the skin is also delayed.