Chitosan-Cross-linked Osmium Polymer Composites as an Efficient Platform for Electrochemical Biosensors

Authors

  • Dr. Harishchandra Digambar Jirimali,

    1. Department of Chemistry and Interdisciplinary Program of Integrated Biotechnology, Sogang University, Seoul 121-742 Republic of Korea
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  • Dr. Rajaram Krishna Nagarale,

    1. Department of Chemistry and Interdisciplinary Program of Integrated Biotechnology, Sogang University, Seoul 121-742 Republic of Korea
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  • Dr. Jong Myung Lee,

    1. Department of Chemistry and Interdisciplinary Program of Integrated Biotechnology, Sogang University, Seoul 121-742 Republic of Korea
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  • Dr. Durai Saravanakumar,

    1. Department of Chemistry and Interdisciplinary Program of Integrated Biotechnology, Sogang University, Seoul 121-742 Republic of Korea
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  • Prof. Dr. Woonsup Shin

    Corresponding author
    1. Department of Chemistry and Interdisciplinary Program of Integrated Biotechnology, Sogang University, Seoul 121-742 Republic of Korea
    • Department of Chemistry and Interdisciplinary Program of Integrated Biotechnology, Sogang University, Seoul 121-742 Republic of Korea

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Abstract

A new family of chitosan-cross-linked osmium polymer composites was prepared and its electrochemical properties were examined. The composites were prepared by quaternization of the poly(4-vinylpyridine) osmium bipyridyl polymer (PVP-Os) which was then cross-linked with chitosan, yielding PVP-Os/chitosan. Films made of the composites showed improved mass and electron transport owing to the porous and hydrophilic structure which is derived from the cross-links between the Os polymer and chitosan. The rate for glucose oxidation was enhanced four times when glucose oxidase (GOx) was immobilized on PVP-Os/chitosan compared immobilization on PVP-Os.

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