Porosity-Controlled Eggshell Membrane as 3D SERS-Active Substrate

Authors

  • Pei-Ying Lin,

    1. Department of Chemistry and Center for Nanoscience and Nanotechnology, National Sun Yat-sen University, Kaohsiung 80424 (Taiwan), Tel: (+886) 75252000 ext. 3931, Fax: (+886) 75253908
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  • Chiung-Wen Hsieh,

    1. Department of Chemistry and Center for Nanoscience and Nanotechnology, National Sun Yat-sen University, Kaohsiung 80424 (Taiwan), Tel: (+886) 75252000 ext. 3931, Fax: (+886) 75253908
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  • Pei-Chuan Tsai,

    1. Department of Chemistry and Center for Nanoscience and Nanotechnology, National Sun Yat-sen University, Kaohsiung 80424 (Taiwan), Tel: (+886) 75252000 ext. 3931, Fax: (+886) 75253908
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  • Prof. Shuchen Hsieh

    Corresponding author
    1. Department of Chemistry and Center for Nanoscience and Nanotechnology, National Sun Yat-sen University, Kaohsiung 80424 (Taiwan), Tel: (+886) 75252000 ext. 3931, Fax: (+886) 75253908
    2. School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708 (Taiwan)
    • Department of Chemistry and Center for Nanoscience and Nanotechnology, National Sun Yat-sen University, Kaohsiung 80424 (Taiwan), Tel: (+886) 75252000 ext. 3931, Fax: (+886) 75253908===

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  • SERS=Surface-enhanced Raman scattering

Abstract

We report on the fabrication of a surface-enhanced Raman scattering (SERS) platform, comprised of a three-dimensional (3D) porous eggshell membrane (ESM) scaffold decorated with Ag nanoparticles (NPs). Both native and treated ESM were used, where the treated ESM pore size and fiber crossing density was controlled by timed exposure to hydrogen peroxide (H2O2). Ag NPs were synthesized in situ by reduction of silver nitrate with ascorbic acid. Our results demonstrate that H2O2-treated Ag-ESM provides a more densely packed 3D network of active material, which leads to consistently higher SERS enhancement than untreated Ag-ESM substrates.

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