Online Monitoring of Intelligent Polymers for Drug Release with Hyperpolarized Xenon (pages 4120–4123)
Stefan Glöggler, Markus Raue, Johannes Colell, Pierre Türschmann, Alexander Liebisch, Prof. Thomas Mang, Prof. Bernhard Blümich and Prof. Stephan Appelt
Article first published online: 19 NOV 2012 | DOI: 10.1002/cphc.201200658
Welcome to the guest zone: By combining hyperpolarized xenon and simple low-field NMR devices it is possible to obtain more control over hydrogels that show potential as drug delivery systems. An alternative way of polymer swelling-degree determination is demonstrated with real-time NMR analysis. An ideal region for solvent uptake can be defined in which the absorbed solvent molecules are completely confined in the nano-porous network of the hydrogel.