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Biochemistry and Physiology of Cholinergic Transmission

Handbook of Physiology, The Nervous System, Cellular Biology of Neurons

  1. B. Collier

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp010113

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Collier, B. 2011. Biochemistry and Physiology of Cholinergic Transmission. Comprehensive Physiology. 463–492.

Author Information

  1. Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Acetylcholine Synthesis
    • 1.1
      Distribution of Choline Acetyltransferase
    • 1.2
      Properties of Choline Acetyltransferase
    • 1.3
      Inhibitors of Choline Acetyltransferase
    • 1.4
      Source of Substrates
    • 1.5
      Regulation
    • 1.6
      Long-term Regulation
  • 2
    Acetylcholine Storage and Release
    • 2.1
      In Brain
    • 2.2
      In Ganglia and Skeletal Muscle
    • 2.3
      In Smooth Muscle
    • 2.4
      In Torpedo Electroplaques
    • 2.5
      Mechanism of Acetylcholine Release
  • 3
    Disposition of Acetylcholine
    • 3.1
      Enzymatic Destruction
    • 3.2
      Acetylcholine Uptake
    • 3.3
      Diffusion