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Cellular Aspects of Catecholaminergic Neurons

Handbook of Physiology, The Nervous System, Cellular Biology of Neurons

  1. L. B. Geffen1,
  2. B. Jarrott2

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp010115

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Geffen, L. B. and Jarrott, B. 2011. Cellular Aspects of Catecholaminergic Neurons. Comprehensive Physiology. 521–571.

Author Information

  1. 1

    School of Medicine, Flinders University of South Australia, Bedford Park, Australia

  2. 2

    Department of Clinical Pharmacology, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Terminology
  • 2
    Historical Developments
    • 2.1
      Identification of the Sympathetic Transmitter
    • 2.2
      Tissue Receptors
    • 2.3
      Autonomic Neuroeffector Junctions
    • 2.4
      Biochemical Mechanisms
  • 3
    Distribution and Storage of Catecholamines
    • 3.1
      Tissue Distribution
    • 3.2
      Cellular Distribution of Catecholamines
    • 3.3
      Subcellular Distribution
    • 3.4
      Quantitative Aspects of Transmitter Distribution
    • 3.5
      Summary
  • 4
    Enzymes Involved in Catecholamine Metabolism
    • 4.1
      Biosynthetic Ezymes
    • 4.2
      Degradative Enzymes
    • 4.3
      Regulation of Catecholamine Turnover
    • 4.4
      Summary
  • 5
    Release and Inactivation of Catecholamines
    • 5.1
      Quantal Liberation of Transmitter by Exocytosis
    • 5.2
      Inactivation of Transmitter
    • 5.3
      Circulating Catecholamines and Dopamine β-hydroxy lase
  • 6
    Adrenotropic Receptors
    • 6.1
      Classification of Adrenotropic Receptors
    • 6.2
      Receptor Topography
    • 6.3
      Receptor Composition
  • 7
    Life Cycle of Noradrenergic Synaptic Vesicles
    • 7.1
      Origin of Vesicles Within Noradrenergic Neurons
    • 7.2
      Turnover and Fate of Synaptic Vesicles
    • 7.3
      Topochemical Model of Noradrenergic Transmission