Standard Article

Specificity of Neurons and their Interconnections

Handbook of Physiology, The Nervous System, Cellular Biology of Neurons

  1. Alan D. Grinnell

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp010122

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Grinnell, A. D. 2011. Specificity of Neurons and their Interconnections. Comprehensive Physiology. 803–853.

Author Information

  1. Departments of Biology and Physiology, University of California at Los Angeles, Los Angeles, California

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    The Individuality of Nerve Cells and the Precision of Connections
    • 1.1
      Invertebrates
    • 1.2
      Vertebrates
  • 2
    Genetic Approaches to Connectivity and Nerve Function
    • 2.1
      Development Without Experience
    • 2.2
      Precision of Connectivity in Genetically Identical Organisms
    • 2.3
      Mutant Analysis
  • 3
    Experimental Analysis of the Specification of Connections
    • 3.1
      Examples of Nonspecific Synapse Formation
    • 3.2
      Specificity of Neuromuscular Connectivity in Vertebrates
    • 3.3
      Specification of Properties of Neuromuscular Connections and Their Regeneration in Invertebrates
    • 3.4
      Specificity of Regeneration of Sensory Nerves to Peripheral Structures
    • 3.5
      Specificity of Regeneration of Retinotectal Connections in Lower Vertebrates
  • 4
    Plasticity in Connectivity; Critical Periods
    • 4.1
      Effects of Visual Deprivation
    • 4.2
      Critical Period
    • 4.3
      Evidence for Competition Between Lateral Geniculate Neurons
    • 4.4
      Role of Experience in Development
    • 4.5
      Function of the Critical Period
    • 4.6
      Xenopus Ipsilateral Projection
    • 4.7
      Theoretical Need for Coherence of Activity
    • 4.8
      Morphological Correlates of Deprivation and Plasticity
  • 5
    Chemoaffinity and the Specificity of Neural Development and Regeneration
    • 5.1
      Gradients and Developmental Timing
    • 5.2
      Tissue Culture Approaches
    • 5.3
      Electron-microscopic Reconstruction of Development and Glial Guidance
    • 5.4
      Chemical Interactions Governing Differentiation
    • 5.5
      Cell-specific Macromolecules and Selective Adhesion
  • 6
    Summary