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Spinal Neurons and Synapses

Handbook of Physiology, The Nervous System, Cellular Biology of Neurons

  1. R. E. Burke1,
  2. P. Rudomin2

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp010124

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Burke, R. E. and Rudomin, P. 2011. Spinal Neurons and Synapses. Comprehensive Physiology. 877–944.

Author Information

  1. 1

    Laboratory of Neural Control, National Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health, Bethesda, Maryland

  2. 2

    Department of Physiology, Centro de Investigacion y de Estudios Avanzados, Instituto Politecnico Nacional, Mexico, D. F., Mexico

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    I. Motoneurons
    • 1.1
      A. Alpha Motoneurons
    • 1.2
      Gamma Motoneurons
  • 2
    II. Interneurons
    • 2.1
      A. General Considerations
    • 2.2
      B. Functionally Identified Interneuron Systems
  • 3
    III. Tract Cells
    • 3.1
      General Considerations
    • 3.2
      B. Specific Systems
  • 4
    IV. Intraspinal Primary Afferents and Presynaptic Modulation
    • 4.1
      A. General Considerations
    • 4.2
      B. Intrinsic Properties of Intraspinal Afferents
    • 4.3
      C. Evidence for the Existence of Primary Afferent Depolarization (PAD)
    • 4.4
      D. Afferent Terminals Are Subjected Only to Depolarizing Input
    • 4.5
      E. Interneurons Are Involved in the Mechanism of PAD Generation
    • 4.6
      F. Possible Mechanisms of PAD Production by Interneurons
    • 4.7
      G. Changes in Synaptic Transmission Related to PAD
    • 4.8
      H. Possible Mechanisms for Presynaptic Inhibition
    • 4.9
      I. Consequences of Presynaptic Modulation of Synaptic Transmission
    • 4.10
      J. Organization of PAD
  • 5
    V. Concluding Comment