Standard Article

Neuronal Plasticity and the Modification of Behavior

Handbook of Physiology, The Nervous System, Cellular Biology of Neurons

  1. Eric R. Kandel

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp010129

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Kandel, E. R. 2011. Neuronal Plasticity and the Modification of Behavior. Comprehensive Physiology. 1137–1182.

Author Information

  1. Division of Neurobiology and Behavior, Departments of Physiology and Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Strategies in Neuronal Studies of Behavioral Modifications
    • 1.1
      Dynamic and Plastic Capabilities of Synaptic Pathways
    • 1.2
      Plasticity Hypothesis
    • 1.3
      Dynamic Hypothesis
  • 2
    Synaptic Mechanisms of Plastic Change: Potentiation and Depression
    • 2.1
      Posttetanic Potentiation: Enhancement of Synaptic Transmission Following Use
    • 2.2
      Tenotomy: Enhancement of Synaptic Transmission Through Disuse
    • 2.3
      Depression of Synaptic Pathways Following Use
    • 2.4
      Plastic Capabilities of Electrical and Chemical Synapses
    • 2.5
      Plastic Capabilities of the Chemical Synapses of Invertebrates
    • 2.6
      Heterosynaptic Facilitation, Depression, and Sprouting
  • 3
    Nonsynaptic Mechanisms of Plastic Change
  • 4
    Biochemical Aspects of Neuronal Plasticity
  • 5
    Morphological Aspects of Neuronal Plasticity
  • 6
    Relation of Neuronal Plasticity to Behavioral Modifications
  • 7
    Cellular Studies of Behavioral Modifications in the Immature Nervous System
    • 7.1
      Development of Connections in the Visual System
    • 7.2
      Effects of Light and Pattern Deprivation in Newborn Animals on Functional Interconnections of Cells in the Visual System
  • 8
    Cellular Studies of Behavioral Modifications in Mature Animals
    • 8.1
      Habituation and Dishabituation
    • 8.2
      Flexion Withdrawal in the Cat
    • 8.3
      Gill Withdrawal in Aplysia
    • 8.4
      Escape Swimming in Crayfish
    • 8.5
      Escape Response in the Cockroach
    • 8.6
      Short-Term Synaptic Plasticity and Short-Term Habituation
  • 9
    Mechanistic Relationships Among Simple Behavioral Modifications
    • 9.1
      Relationship of Habituation to Dishabituation
    • 9.2
      Relationship of Short- to Long-term Memory
    • 9.3
      Relationship of Long-term Sensitization to Behavioral Abnormalities
    • 9.4
      Relationship of Habituation to Higher Forms of Learning
  • 10
    Complex Behavioral Modifications: Classical Conditioning
    • 10.1
      Classical Conditioning in the Isolated Spinal Cord
    • 10.2
      Classical Conditioning of the Eye-blink Response
    • 10.3
      Classical Conditioning in Simple Invertebrates: Feeding in Gastropod Molluscs
  • 11
    Overview