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Histaminergic Transmission in the Brain

Handbook of Physiology, The Nervous System, Intrinsic Regulatory Systems of the Brain

  1. Jean-Charles Schwartz,
  2. Monique Garbarg,
  3. Héléne Pollard

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp010405

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Schwartz, J.-C., Garbarg, M. and Pollard, H. 2011. Histaminergic Transmission in the Brain. Comprehensive Physiology. 257–316.

Author Information

  1. Unité de Neurobiologie, Centre Paul Broca de l'Institut National de la Santé et de la Recherche Médicale, Paris, France

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Metabolism of Histamine in Brain
    • 1.1
      Biosynthesis
    • 1.2
      Storage
    • 1.3
      Release
    • 1.4
      Inactivation
    • 1.5
      Turnover
  • 2
    Identification of Histaminergic Neuronal Pathways by Lesion Studies
    • 2.1
      Evidence for Histaminergic Pathway in Medial Forebrain Bundle
    • 2.2
      Studies of Histaminergic Afferents in Hippocampal and Amygdaloid Regions
    • 2.3
      Attempts at Localizing Origin of Histaminergic Pathways
  • 3
    Immunohistochemical Localization of Histaminergic Neuronal Pathways
    • 3.1
      Various Immunohistochemical Tools
    • 3.2
      Localization of Immunoreactive Cell Bodies
    • 3.3
      Histaminergic Neuronal Projections and Areas of Terminations
  • 4
    Histamine Receptors and Actions in Brain
    • 4.1
      Pharmacological Tools for Identification of Subclasses of Histamine Receptors
    • 4.2
      Radioligand Binding Studies of Histamine Receptors
    • 4.3
      Histamine Receptors Linked to cAMP Formation
    • 4.4
      Histamine-Induced Glycogenolysis
    • 4.5
      Other Biochemical Responses to Histamine Mediated by H1 Receptors
    • 4.6
      Electrophysiological Investigation of Histamine Actions in Brain
    • 4.7
      Neuroendocrine Responses to Histamine
    • 4.8
      Vegetative Responses to Histamine
    • 4.9
      Effects of Histamine on Vascular Regulation in Brain
  • 5
    Conclusion