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Neuronal Basis of Behavioral State Control

Handbook of Physiology, The Nervous System, Intrinsic Regulatory Systems of the Brain

  1. J. A. Hobson1,
  2. M. Steriade2

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp010414

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Hobson, J. A. and Steriade, M. 2011. Neuronal Basis of Behavioral State Control. Comprehensive Physiology. 701–823.

Author Information

  1. 1

    Laboratory of Neurophysiology, Department of Psychiatry, Harvard Medical School, Boston, Massachusetts

  2. 2

    Laboratory of Neurophysiology, Department of Physiology, School of Medicine, Université Laval, Quebec, Canada

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Behavioral States and Biological Rhythms
    • 1.1
      State Concept and Definition of Some Behavioral States
    • 1.2
      Neuronal Correlates of Behavioral States and Their Interpretation as Causes
    • 1.3
      Temporal Aspects of Behavioral States
    • 1.4
      Circadian Rhythms and Behavioral State Control
  • 2
    Anatomical Substrates of Regulatory Systems
    • 2.1
      Changing the Concept of Nonspecificity
    • 2.2
      Brain Stem Reticular Formation
    • 2.3
      Thalamoneocortical Systems Related to Ascending Reticular Influences
    • 2.4
      Monoaminergic Systems
  • 3
    Brain Stem Core Systems Regulating Forebrain Activation
    • 3.1
      Definition of Activation
    • 3.2
      Search for Critical Regions at Global Level: Lesion-Stimulation Studies
    • 3.3
      Criteria of Cellular Evaluation
    • 3.4
      Search for Candidate Mechanisms at Single-Cell Level
  • 4
    Thalamocortical Mechanisms Related to Activation and Deactivation Processes
    • 4.1
      Spontaneous Activity
    • 4.2
      Excitatory-Inhibitory Response Sequence
    • 4.3
      Excitability Enhancement During Attentional Tasks
    • 4.4
      Neurons and Transmitters Responsible for Thalamocortical Activation Processes
  • 5
    Sleep Cycle
    • 5.1
      Definition and Phenomenology
    • 5.2
      Cellular Correlates of Cycle
    • 5.3
      Pontine Localization of Desynchronized-Sleep Trigger and Clock
    • 5.4
      Aminergic Hypothesis
    • 5.5
      Reciprocal Interaction Model of Sleep-Cycle Control
    • 5.6
      Neuropharmacology of Sleep Cycle
  • 6
    Physiology and Pathophysiology of Sleep in Humans
    • 6.1
      Pathophysiological Model of Human Disorders
    • 6.2
      Pathophysiology of Narcolepsy
    • 6.3
      Pathophysiology of Sleep Apnea Syndromes
    • 6.4
      Disturbances of Motor Activity in Sleep
    • 6.5
      Dreaming and Disturbances of Mental Activity in Sleep
  • 7
    Functional Significance of Sleep and Waking States
    • 7.1
      General Adaptational Advantages of Rhythmic State Alternations
    • 7.2
      Rest Theory of Sleep
    • 7.3
      Development Implications of REM Sleep as Internal Activation Process
    • 7.4
      States and Acquisition of Learned Aspects of Adaptive Behavior
    • 7.5
      States and Metabolic Mode of the Brain
  • 8
    Conclusions