Standard Article

Circulatory and Metabolic Correlates of Brain Function in Normal Humans

Handbook of Physiology, The Nervous System, Higher Functions of the Brain

  1. Marcus E. Raichle

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp010516

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Raichle, M. E. 2011. Circulatory and Metabolic Correlates of Brain Function in Normal Humans. Comprehensive Physiology. 643–674.

Author Information

  1. Edward Mallinckrodt Institute of Radiology, Department of Neurology and Neurological Surgery, and McDonnell Center for Studies of Higher Brain Function, Washington University School of Medicine, St. Louis, Missouri

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Methods
    • 1.1
      Tracer Strategies
    • 1.2
      Instrumentation
    • 1.3
      Anatomical Localization Procedures
    • 1.4
      Statistical Considerations
  • 2
    Relationship of Neuronal Activity to Blood Flow and Energy Metabolism
    • 2.1
      Neuronal Function and Energy Metabolism
    • 2.2
      Blood Flow and Energy Metabolism
    • 2.3
      Effect of Elementary Stimulus Variables
  • 3
    Resting Awake Brain: Changes in Blood Flow and Metabolism
    • 3.1
      Normal Features
    • 3.2
      Sleep
    • 3.3
      Anxiety
    • 3.4
      Age
    • 3.5
      Anatomical Asymmetries and Atrophy
  • 4
    Activated Brain: Changes in Blood Flow and Metabolism
    • 4.1
      Voluntary Motor Activity
    • 4.2
      Somatosensory Stimulation
    • 4.3
      Visual Stimulation
    • 4.4
      Auditory Stimulation
    • 4.5
      Speech and Language
    • 4.6
      Mental Work
  • 5
    Conclusions