Standard Article

Neural Correlates of Cognitive Impairment in Alzheimer's Disease

Handbook of Physiology, The Nervous System, Higher Functions of the Brain

  1. Gary W. Van Hoesen,
  2. Antonio R. Damasio

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp010522

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Van Hoesen, G. W. and Damasio, A. R. 2011. Neural Correlates of Cognitive Impairment in Alzheimer's Disease. Comprehensive Physiology. 871–998.

Author Information

  1. Departments of Anatomy and Neurology, University of Iowa College of Medicine, Iowa City, Iowa

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Historical Perspective
    • 1.1
      Diagnostic Criteria
    • 1.2
      Epidemiological and Genetic Studies
    • 1.3
      Disease Status of AD
  • 2
    Neuropsychological Studies
    • 2.1
      Impairments of Memory
    • 2.2
      Impairments of Executive Control and Problem Solving
    • 2.3
      Impairments of Language
    • 2.4
      Impairments of Praxis and Spatial Processing
    • 2.5
      Impairment of Attention
  • 3
    Conceptualizing Cognitive Impairments of AD in Terms of Neural Systems
  • 4
    Neuroanatomical Perspective on AD
    • 4.1
      Cortical Architecture and Connectivity in Primates
    • 4.2
      Topographical Distribution of Pathological Changes in AD in Relation to Cortical Types
    • 4.3
      Cortical Laminar Specificity and Patterns of Pathology in AD
    • 4.4
      Anatomical Changes in Subcortical Structures in AD
  • 5
    Neurochemical Changes in AD
  • 6
    Neuroimaging Studies
  • 7
    Concluding Remarks