Standard Article

Cellular Basis of Physiological and Pathological Myocardial Growth

Handbook of Physiology, The Cardiovascular System, The Heart

  1. Piero Anversa,
  2. Giorgio Olivetti

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp020102

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Anversa, P. and Olivetti, G. 2011. Cellular Basis of Physiological and Pathological Myocardial Growth. Comprehensive Physiology. 75–144.

Author Information

  1. Department of Medicine, New York Medical College, Valhalla, New York

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Morphometric Analysis of Cell Size and Number in the Ventricular Myocardium
    • 1.1
      Myocyte Dimensional Properties and Number: Methodological Considerations
    • 1.2
      Confocal Microscopic Measurements of Myocyte Cell Volume
  • 2
    Morphometric Analysis of the Coronary Vasculature
  • 3
    Physiological Myocardial Growth: Maturation of the Heart
    • 3.1
      Ventricular Remodeling
    • 3.2
      Myocyte Adaptations
    • 3.3
      Cytoplasmic Adaptations in Myocytes
    • 3.4
      Capillary Adaptations
    • 3.5
      Conclusions
  • 4
    Aging of the Heart
    • 4.1
      Aging and Ventricular Remodeling
    • 4.2
      Aging and Myocyte Number
    • 4.3
      Aging and Myocyte Reactive Hypertrophy
    • 4.4
      Aging and the Coronary Arterial and Capillary Tree
    • 4.5
      Conclusions
  • 5
    Pressure and Volume Overload Hypertrophy
    • 5.1
      Cardiac Hypertrophy and Ventricular Remodeling
    • 5.2
      Cardiac Hypertrophy and Myocyte Size, Shape, and Number
    • 5.3
      Cardiac Hypertrophy and Volume Composition of Myocytes
    • 5.4
      Cardiac Hypertrophy and the Coronary Arterial and Capillary Tree
    • 5.5
      Conclusions
  • 6
    Ischemic Cardiomyopathy
    • 6.1
      Ischemic Cardiomyopathy and Ventricular Remodeling
    • 6.2
      Ischemic Cardiomyopathy, Myocyte Cell Loss, and Ventricular Function
    • 6.3
      Ischemic Cardiomyopathy and Myocyte Cellular Hypertrophy and Hyperplasia
    • 6.4
      Ischemic Cardiomyopathy and Volume Composition of Myocytes
    • 6.5
      Ischemic Cardiomyopathy and the Coronary Capillary Tree
    • 6.6
      Conclusions