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Lysosomes in Vascular Smooth Muscle Cells

Handbook of Physiology, The Cardiovascular System, Vascular Smooth Muscle

  1. Stanley Fowler1,
  2. Harvey Wolinsky2

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp020206

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Fowler, S. and Wolinsky, H. 2011. Lysosomes in Vascular Smooth Muscle Cells. Comprehensive Physiology. 133–160.

Author Information

  1. 1

    Laboratory of Biochemical Cytology, The Rockefeller University, New York, New York

  2. 2

    Departments of Medicine and Pathology, The Albert Einstein College of Medicine, Bronx, New York

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    General Properties of Lysosomes
    • 1.1
      Definition
    • 1.2
      Physiological Functions of Lysosomes
  • 2
    Methods Used to Study Lysosomes
    • 2.1
      Biochemical Techniques
    • 2.2
      Morphological Techniques
  • 3
    Lysosomes in Vascular Smooth Muscle
    • 3.1
      Properties of Lysosomes in Aortic Smooth Muscle Cells
    • 3.2
      Lysosmal Alterations Associated with Vascular Diseases
  • 4
    Lysosomal Functions in Vascular Smooth Muscle Cells and Implications for Disease
    • 4.1
      Implications for Atherosclerosis
    • 4.2
      Implications for Hypertension and Diabetes Mellitus
    • 4.3
      Possible Implications of Autophagy
    • 4.4
      Insights from Inborn States of Lysosomal Deficiency
  • 5
    Conclusion
  • 6
    Addendum