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Adrenergic Regulation of Vascular Smooth Muscle

Handbook of Physiology, The Cardiovascular System, Vascular Smooth Muscle

  1. John A. Bevan,
  2. Rosemary D. Bevan,
  3. Sue P. Duckles

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp020218

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Bevan, J. A., Bevan, R. D. and Duckles, S. P. 2011. Adrenergic Regulation of Vascular Smooth Muscle. Comprehensive Physiology. 515–566.

Author Information

  1. Brain Research Institute and Department of Pharmacology, School of Medicine, Center for Health Sciences, University of California, Los Angeles, California

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Morphology of Adrenergic Innervation
  • 2
    Adrenergic Transmission: Presynaptic and Synaptic Events
    • 2.1
      Transmitter Synthesis, Storage, and Release
    • 2.2
      Mode of Transmitter Release
    • 2.3
      Feedback Control of Transmitter Release
    • 2.4
      Transmitter Distribution and Movement
    • 2.5
      Transmitter Concentrations During Neural Activity
    • 2.6
      Transmitter Disposition and Termination of Its Effect
  • 3
    Adrenergic Transmission: Postsynaptic Events
    • 3.1
      Receptor Analysis and Variation
    • 3.2
      Bimodal Transmitter Action
    • 3.3
      Contractile Properties of Endothelium
  • 4
    Functional Consequences of Variation in Vascular Neuroeffector Apparatus
    • 4.1
      Synaptic Cleft Width
    • 4.2
      Innervation Density
    • 4.3
      Innervation Distribution
  • 5
    Functional Description of Specific Vessels
  • 6
    Adrenergic Neuron in Hypertension
    • 6.1
      Changes in Presynaptic Mechanisms
    • 6.2
      Neurogenic Transmission and Postsynaptic Function
    • 6.3
      Distribution of Adrenergic Transmitter in Hypertensive Arteries
    • 6.4
      Plasma Norepinephrine and Dopamine β-Hydroxylase Levels
    • 6.5
      Interpretation of Changes in Adrenergic Mechanisms
  • 7
    Development of Adrenergic Control: Trophic Regulation
    • 7.1
      Ontogenetic Development of Innervation of Blood Vessels
    • 7.2
      Specificity of Adrenergic Innervation of Blood Vessels
    • 7.3
      Smooth Muscle Specificity for Nerve
    • 7.4
      Interactions of Nerve and Smooth Muscle
    • 7.5
      Influence of Adrenergic Nerves on Smooth Muscle
    • 7.6
      Influence of Smooth Muscle on Adrenergic Nerves
    • 7.7
      Factors Influencing Development and Maturation of Peripheral Sympathetic Nerve Terminals
    • 7.8
      Regulation of Sympathetic Function in Adults
    • 7.9
      Morphological and Functional Plasticity of Adrenergic Neurons