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Cerebral Circulation

Handbook of Physiology, The Cardiovascular System, Peripheral Circulation and Organ Blood Flow

  1. Donald D. Heistad1,
  2. Hermes A. Kontos2

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp020305

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Heistad, D. D. and Kontos, H. A. 2011. Cerebral Circulation. Comprehensive Physiology. 137–182.

Author Information

  1. 1

    Department of Medicine and Cardiovascular Center, University of Iowa College of Medicine and Veterans Administration Medical Center, Iowa City, Iowa

  2. 2

    Department of Medicine, Medical College of Virginia, Richmond, Virginia

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Anatomy
    • 1.1
      Arterial System
    • 1.2
      Capillaries, Veins, and Lymphatics
    • 1.3
      Blood-Brain Barrier
    • 1.4
      Choroid Plexus and Cerebrospinal Fluid
  • 2
    Methods
    • 2.1
      Direct Observation of Pial Vessels
    • 2.2
      Venous Outflow Techniques
    • 2.3
      Cerebral Arterial Inflow
    • 2.4
      Diffusible Indicators
    • 2.5
      Measurement of Clearance With Electrodes
    • 2.6
      Autoradiography
    • 2.7
      Microspheres
    • 2.8
      Experimental Comparison of Methods
  • 3
    Distribution of Segmental Vascular Resistance
  • 4
    Neural Regulation
    • 4.1
      Innervation
    • 4.2
      Neurotransmitters and Neuromuscular Mechanisms
    • 4.3
      Effects of Sympathetic Nerves
    • 4.4
      Effects of Cholinergic and Peptidergic Nerves
    • 4.5
      Reflex Effects of Sympathetic Nerves
    • 4.6
      Role of Central Neural Pathways
  • 5
    Chemical Regulation
    • 5.1
      Effects of Carbon Dioxide and Hydrogen Ion on Cerebral Vessels
    • 5.2
      Effects of Arterial Blood Pco2 on Cerebral Blood Flow
    • 5.3
      Effects of Oxygen on Cerebral Vessels
    • 5.4
      Effects of Oxygen on Cerebral Blood Flow
    • 5.5
      Angiotensin, Vasopressin, Oxytocin, and Prostaglandins
  • 6
    Metabolic Regulation
    • 6.1
      Relationship of Cerebral Function and Blood Flow
    • 6.2
      Cerebral Function and Metabolism
    • 6.3
      Correlation Between Cerebral Blood Flow and Metabolism
    • 6.4
      Mechanisms by Which Metabolism Influences Cerebral Blood Flow
    • 6.5
      Autoregulation
    • 6.6
      Effects of Atherosclerosis
    • 6.7
      Effects of Changes in Hematocrit and Blood Viscosity
  • 7
    Conclusion