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Blood Flow in Microvascular Networks

Handbook of Physiology, The Cardiovascular System, Microcirculation

  1. Axel R. Pries1,2,
  2. Timothy W. Secomb3

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp020401

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Pries, A. R. and Secomb, T. W. 2011. Blood Flow in Microvascular Networks. Comprehensive Physiology. 3–36.

Author Information

  1. 1

    Department of Physiology, Charité Berlin CBF, Arnimallee, Berlin, Germany

  2. 2

    German Heart Center Berlin, Augustenburger Platz, Berlin, Germany

  3. 3

    Department of Physiology, University of Arizona, Tucson, AZ, USA

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Introduction
  • 2
    Flow in Single Microvessels
    • 2.1
      Flow Resistance, Poiseuille's Law, and Effective Viscosity
    • 2.2
      Fåhraeus Effect
    • 2.3
      Fåhraeus-Lindqvist Effect
    • 2.4
      Aggregation and Sedimentation
    • 2.5
      Endothelial Surface Layer
    • 2.6
      Effective Blood Viscosity in vivo
  • 3
    Microvascular Networks
    • 3.1
      General Features
    • 3.2
      Topology
    • 3.3
      Topological Growth Models
    • 3.4
      Segment Lengths and Diameters
    • 3.5
      Heterogeneity and Correlations
    • 3.6
      Flow and Transit Time
    • 3.7
      Pressure and Wall Stresses
    • 3.8
      Phase Separation in Bifurcations
    • 3.9
      Network Fåhraeus Effect
  • 4
    Relationship of Network Structure and Flow to Physiological Functions
    • 4.1
      Transport Functions
    • 4.2
      Inflammatory and Immune Functions
    • 4.3
      Regulation of Blood Flow
    • 4.4
      Structural Adaptation
  • 5
    Conclusions