Standard Article

Microvascular Consequences of Obesity and Diabetes

Handbook of Physiology, The Cardiovascular System, Microcirculation

  1. H Glenn Bohlen

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp020419

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Bohlen, H. G. 2011. Microvascular Consequences of Obesity and Diabetes. Comprehensive Physiology. 896–930.

Author Information

  1. Department of Cellular and Integrative Physiology, Indiana University Medical School, Barnhill Drive, Indianapolis, IN, USA

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Major Differences in Insulin-Dependent and-Independent Diabetes
  • 2
    Consequences of Obesity
  • 3
    Insulin Receptor-no Production in Obesity and Diabetes
  • 4
    Functional Studies of no Mechanisms in Obesity, Hyperglycemia, and Diabetes
  • 5
    Blood Lipids and Endothelial Function
  • 6
    Vascular Smooth Muscle Function in Obesity and Diabetes
    • 6.1
      Leptin and C-peptide influences on vascular regulation in obesity and diabetes
    • 6.2
      Hyperglycemia as a major threat to vascular function
    • 6.3
      Hyperglycemia, PKC, and NO
    • 6.4
      Oxygen radical formation during hyperglycemia
  • 7
    Conclusions
    • 7.1
      The state of affairs
    • 7.2
      The future
  • 8
    Acknowledgments