Standard Article

Pulmonary Interstitial Spaces and Lymphatics

Handbook of Physiology, The Respiratory System, Circulation and Nonrespiratory Functions

  1. Aubrey E. Taylor,
  2. James C. Parker

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp030104

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Taylor, A. E. and Parker, J. C. 2011. Pulmonary Interstitial Spaces and Lymphatics. Comprehensive Physiology. 167–230.

Author Information

  1. Department of Physiology, University of South Alabama School of Medicine, Mobile, Alabama

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Structure and Composition of Pulmonary Interstitium
    • 1.1
      Pulmonary Interstitial Connective Tissues
    • 1.2
      Physicochemical Properties of Interstitial Matrix
    • 1.3
      Vascular and Extravascular Fluid Compartments in the Lung
    • 1.4
      Effect of Increased Hydration on Tissue Fluid Compartments
  • 2
    Starling Forces and Lymph Flow
    • 2.1
      Theoretical Considerations
    • 2.2
      Endothelial Pathways
    • 2.3
      Filtration Coefficient
    • 2.4
      Capillary Pressure
    • 2.5
      Tissue Fluid Pressure
    • 2.6
      Estimation of Intra-Alveolar Fluid Pressure by Analysis of Structure
    • 2.7
      Interstitial Compliance
    • 2.8
      Interstitial Fluid Pressure Gradients
    • 2.9
      Colloid Osmotic Pressure Gradient
    • 2.10
      Lymph Flow
    • 2.11
      Analyses of Force Changes During Formation of Alveolar Edema: Edema Safety Factor
  • 3
    Abnormal Capillary Permeability to Plasma Proteins (Leaky Lung Syndromes)
    • 3.1
      α-Naphthylthiourea
    • 3.2
      Hydrochloric Acid Aspiration
    • 3.3
      Hemorrhagic Shock
    • 3.4
      Septic Shock
    • 3.5
      Histamine
    • 3.6
      High-Altitude Pulmonary Edema
    • 3.7
      Neurogenic Pulmonary Edema
    • 3.8
      Microemboli Vascular Damage
    • 3.9
      Oxygen Toxicity
    • 3.10
      Other Compounds
    • 3.11
      Possible Mechanisms: Superoxide System
  • 4
    Sequence and Pathways for Pulmonary Edema Formation
  • 5
    Conclusions