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Micromechanics of the Lung

Handbook of Physiology, The Respiratory System, Mechanics of Breathing

  1. Ian A. Greaves1,
  2. Jacob Hildebrandt2,
  3. Frederic G. Hoppin Jr.3

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp030314

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Greaves, I. A., Hildebrandt, J. and Hoppin, F. G. 2011. Micromechanics of the Lung. Comprehensive Physiology. 217–231.

Author Information

  1. 1

    Harvard School of Public Health, Boston, Massachusetts

  2. 2

    Virginia Mason Research Center, University of Washington, Seattle, Washington

  3. 3

    The Memorial Hospital, Brown University, Pawtucket, Rhode Island

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Configuration of Terminal Air Spaces
    • 1.1
      Macroscopic Isotropy and Symmetry of Expansion
    • 1.2
      Alveolus–Alveolar Duct Interactions
    • 1.3
      Air-Space Morphometry—Light Microscopy
    • 1.4
      Air-Space Morphometry—Electron Microscopy
  • 2
    Mechanical Interactions of Tissue and Surface
    • 2.1
      Mechanical Models
    • 2.2
      Morphology in Presence and Absence of Surface Tension
    • 2.3
      Effects on Capillaries and Interstitial Fluid
  • 3
    Closure
    • 3.1
      Airways
    • 3.2
      Alveoli
    • 3.3
      Sequence of Closure
  • 4
    Opening
    • 4.1
      Airways
    • 4.2
      Alveoli
    • 4.3
      Mechanics of Opening
    • 4.4
      Septal Pleats
  • 5
    Gas Trapping
    • 5.1
      Foam
    • 5.2
      Mechanism
    • 5.3
      Trapping in Vivo
  • 6
    Instability
    • 6.1
      Negative Pressure- Volume Compliance
    • 6.2
      Configurational Stability
    • 6.3
      Surface Tension Elastance
    • 6.4
      Positive Tissue Elastance
    • 6.5
      Network Behavior (Interdependence)