Standard Article

Inspiratory Muscle Fatigue

Handbook of Physiology, The Respiratory System, Mechanics of Breathing

  1. Charis Roussos1,
  2. Peter T. MacKlem2

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp030329

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Roussos, C. and MacKlem, P. T. 2011. Inspiratory Muscle Fatigue. Comprehensive Physiology. 511–527.

Author Information

  1. 1

    Critical Care Medicine and Meakins-Christie Laboratories, Royal Victoria Hospital, Department of Medicine, McGill University, Montreal, Canada

  2. 2

    Department of Medicine, McGill University and Royal Victoria Hospital, Montreal, Canada

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Muscle Function and Fatigue
    • 1.1
      Force Generation
    • 1.2
      Central Fatigue
    • 1.3
      Peripheral Fatigue
    • 1.4
      Integrated View of Inspiratory Muscle Fatigue
  • 2
    Pathophysiology of Inspiratory Muscle Fatigue
    • 2.1
      Energy Balance—Theoretical Considerations
    • 2.2
      Respiratory Muscle Fatigue and Ventilatory Failure
    • 2.3
      Factors Predisposing to Inspiratory Muscle Fatigue
    • 2.4
      Improvement in Contractility and Endurance
  • 3
    Detection of Respiratory Muscle Fatigue
    • 3.1
      Measurement of Force
    • 3.2
      EMG Spectral Shift
    • 3.3
      Synergic Behavior of the Fatiguing Respiratory Muscles