Standard Article

Effect of Spaceflight on Lymphocyte Function and Immunity

Handbook of Physiology, Environmental Physiology

  1. Felix K. Gmünder1,
  2. Augusto Cogoli2

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp040235

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Gmünder, F. K. and Cogoli, A. 2011. Effect of Spaceflight on Lymphocyte Function and Immunity. Comprehensive Physiology. 799–813.

Author Information

  1. 1

    Basler & Hoffmann Consulting Engineers, Zurich, Switzerland

  2. 2

    Swiss Federal Institute of Technology, Space Biology Group, Zurich, Switzerland

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Lymphocytes
  • 2
    Gravity and Radiation Effects on Lymphocytes
    • 2.1
      In Vitro Gravity Experiments
    • 2.2
      In Vitro Radiation Experiments
  • 3
    Neuroendocrine Control of Lymphocyte Function
  • 4
    Stress Models and Selected Aspects of Immune Function
    • 4.1
      Psychological Stress
    • 4.2
      Physical Exercise
    • 4.3
      Isolation in a Closed Environment
    • 4.4
      Head-down Tilt (HDT) Bed Rest
  • 5
    Animal Models
  • 6
    Space Flight and Selected Aspects of the Immune Function
    • 6.1
      Stress-related Hormones
    • 6.2
      Immunoglobulins
    • 6.3
      Lysozyme
    • 6.4
      Complement
    • 6.5
      White Blood Cell Counts
    • 6.6
      Lymphocyte Subpopulations
    • 6.7
      Natural Killer Cell Activity
    • 6.8
      Lymphocyte Function
  • 7
    Conclusions
  • 8
    Summary