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Neuromuscular transmission in the gastrointestinal tract

Handbook of Physiology, The Gastrointestinal System, Motility and Circulation

  1. Charles H. V. Hoyle,
  2. Geoffrey Burnstock

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp060113

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Hoyle, C. H. V. and Burnstock, G. 2011. Neuromuscular transmission in the gastrointestinal tract. Comprehensive Physiology. 435–464.

Author Information

  1. Department of Anatomy and Developmental Biology and Centre for Neuroscience, University College London, London, United Kingdom

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Electrophysiology of Neuromuscular Transmission
    • 1.1
      Effector Structure
    • 1.2
      Autonomic Neuromuscular Junction
    • 1.3
      Recording Techniques
    • 1.4
      Ion Permeability and Conductance Changes in Effector Smooth Muscle Membrane
  • 2
    Adrenergic Neuromuscular Transmission in the Gastrointestinal Tract
    • 2.1
      Projection of Adrenergic Neurons Within the Muscle Coat
    • 2.2
      Action of Adrenergic Nerves
    • 2.3
      Sphincteric Muscles
    • 2.4
      Nonsphincteric Muscles
    • 2.5
      Adrenergic Neuromodulation
    • 2.6
      Sympathetic Cotransmission in the Gastrointestinal Tract
  • 3
    Transmission From Inhibitory Nerves
    • 3.1
      Inhibitory Junction Potentials
    • 3.2
      Projection of Inhibitory Neurons Within the Gut Wall
    • 3.3
      Putative Inhibitory Neurotransmitters
  • 4
    Transmission From Excitatory Nerves
    • 4.1
      Ionic Basis of Excitatory Junction Potentials
    • 4.2
      Excitatory Neuromuscular Transmitters
  • 5
    Neuromuscular Transmission In Disease States
    • 5.1
      Hirschsprung's Disease
    • 5.2
      Diabetes Mellitus
    • 5.3
      Chronic Constipation and Cathartic Colon
    • 5.4
      Slow-Transit Constipation
    • 5.5
      Ulcerative Colitis
    • 5.6
      Diverticular Disease
    • 5.7
      Irritable Bowel Syndrome
    • 5.8
      Crohn's Disease
    • 5.9
      Summary
  • 6
    Future Directions