Standard Article

Microcirculation of the intestinal mucosa

Handbook of Physiology, The Gastrointestinal System, Motility and Circulation

  1. D. Neil Granger1,
  2. Peter R. Kvietys1,
  3. Ronald J. Korthuis1,
  4. Andre J. Premen2

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp060139

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Granger, D. N., Kvietys, P. R., Korthuis, R. J. and Premen, A. J. 2011. Microcirculation of the intestinal mucosa. Comprehensive Physiology. 1405–1474.

Author Information

  1. 1

    Department of Physiology, Louisiana State University Medical Center, Shreveport, Louisiana

  2. 2

    Department of Physiology, Uniformed Services University of the Health Sciences, F. Edward Hebert School of Medicine, Bethesda, Maryland

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Intrinsic Regulation of Blood Flow and Oxygenation
    • 1.1
      Basic Concepts
    • 1.2
      Vascular Response to Arterial Pressure Alterations
    • 1.3
      Vascular Response to Venous Pressure Elevation
    • 1.4
      Reactive Hyperemia
    • 1.5
      Vascular Response to Alterations in Arterial Blood Gases and Hematocrit
    • 1.6
      Postprandial Intestinal Hyperemia
  • 2
    Influence of Blood Flow on Intestinal Transport
    • 2.1
      Washout of Flow-Limited Solutes
    • 2.2
      Effects of Oxygen Delivery on Absorption
  • 3
    Countercurrent Exchange
    • 3.1
      Anatomical Basis
    • 3.2
      Theoretical Considerations
    • 3.3
      Experimental Evidence
  • 4
    Vascular Capacitance
  • 5
    Vasoactive Agents and Intestinal Oxygen Uptake
    • 5.1
      Relation Between Blood Flow and Oxygen Uptake
    • 5.2
      Oxidative Metabolism
    • 5.3
      Effective Capillary Density
    • 5.4
      Intramural Blood Flow Distribution
  • 6
    Angiotensin II and Vasopressin
  • 7
    Effects of Experimental Conditions on the Intestinal Circulation
    • 7.1
      Anesthesia and Adjuvants
    • 7.2
      Respiration and Blood Gases
    • 7.3
      Laparotomy and Visceral Manipulation
    • 7.4
      Temerature
  • 8
    Transcapillary Fluid and Solute Exchange
    • 8.1
      Starling Hypothesis
    • 8.2
      Rate of Transcapillary Fluid Movement (Lymph Flow)
    • 8.3
      Capillary Filtration Coefficient
    • 8.4
      Capillary Hydrostatic Pressure
    • 8.5
      Interstitial Hydrostatic Pressure
    • 8.6
      Osmotic Reflection Coefficient
    • 8.7
      Transcapillary Oncotic Pressure Gradient
    • 8.8
      Interaction of Capillary and Interstitial Forces
  • 9
    Small-Solute and Macromolecule Exchange
    • 9.1
      Small Solutes
    • 9.2
      Macromolecules
    • 9.3
      Factors Influencing Permeability
    • 9.4
      Pathways for Macromolecule Exchange
  • 10
    Conclusions