Standard Article

Gastrin

Handbook of Physiology, The Gastrointestinal System, Neural and Endocrine Biology

  1. G. J. Dockray,
  2. R. A. Gregory

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp060215

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Dockray, G. J. and Gregory, R. A. 2011. Gastrin. Comprehensive Physiology. 311–336.

Author Information

  1. MRC Secretory Control Research Group, Physiological Laboratory, University of Liverpool, Liverpool, United Kingdom

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Unequivocal Identification of a Pyloric Antral Hormone
  • 2
    Isolation and Characterization of Tissue Forms and Fragments
    • 2.1
      Heptadecapeptide (Little) Gastrin: G-17
    • 2.2
      Big Gastrin: G-34
    • 2.3
      Minigastrin: G-14
    • 2.4
      Small Cooh-Terminal Fragments of G-17
    • 2.5
      Biologically Inactive Forms and Fragments
  • 3
    Molecular Biology—Biosynthesis
  • 4
    Distribution
    • 4.1
      Identification of Gastrin Cells
    • 4.2
      Phylogeny
    • 4.3
      Ontogeny
    • 4.4
      Regulation of G Cell Numbers
  • 5
    Measurement by Radioimmunoassay
    • 5.1
      Antibodies
    • 5.2
      Plasma Forms
    • 5.3
      Gastrin in Antral Venous Outflow: Postsecretory Processing
  • 6
    Metabolism
  • 7
    Release
    • 7.1
      Luminal Mechanisms
    • 7.2
      Hormonal and Paracrine Effects
    • 7.3
      Nervous Control
  • 8
    Actions of Gastrin
    • 8.1
      Trophic Actions
  • 9
    Structure-Function Relationships
    • 9.1
      Cooh-Terminal Fragments
    • 9.2
      Other Gastrin Fragments
    • 9.3
      Antagonists
  • 10
    Receptors