Standard Article

Secretin

Handbook of Physiology, The Gastrointestinal System, Neural and Endocrine Biology

  1. William Y. Chey,
  2. Ta-Min Chang

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp060217

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Chey, W. Y. and Chang, T.-M. 2011. Secretin. Comprehensive Physiology. 359–402.

Author Information

  1. University of Rochester School of Medicine and Dentistry, Department of Medicine, and The Isaac Gordon Center for Digestive Diseases and Nutrition, Genesee Hospital, Rochester, New York

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Discovery of Secretin
    • 1.1
      Historical Background
    • 1.2
      Isolation and Purification of Secretin
    • 1.3
      Structure, Chemical Properties, and Structure-Activity Relationship
    • 1.4
      Synthesis of Secretin
  • 2
    Assay for Secretin
    • 2.1
      Bioassay of Secretin
    • 2.2
      Immunoassays
  • 3
    Distribution of Secretin-Containing Cells
  • 4
    Physiology and Pharmacology of Secretin
    • 4.1
      Release of Secretin
    • 4.2
      Action of Secretin
    • 4.3
      Plasma Half-Life and Catabolism of Secretin
    • 4.4
      Luminal Secretin and Its Biological Action
  • 5
    Mechanism of Action of Secretin
    • 5.1
      Mechanism in Pancreas
    • 5.2
      Mechanism on Stomach
  • 6
    Pathophysiology of Secretin
    • 6.1
      Hypersecretinemia
    • 6.2
      Hyposecretinemia