Standard Article

Gut Glucagon

Handbook of Physiology, The Gastrointestinal System, Neural and Endocrine Biology

  1. Dominique Bataille

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp060220

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Bataille, D. 2011. Gut Glucagon. Comprehensive Physiology. 455–474.

Author Information

  1. Centre CNRS-INSERM de Pharmacologie-Endocrinologie, Montpellier, France

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Gut Glucagon-Related Peptides: Early Studies
  • 2
    Isolation of Glicentin (Proglucagon) and Oxyntomodulin (Glucagon-37)
    • 2.1
      Isolation of Glicentin (Proglucagon)
    • 2.2
      Isolation of Oxyntomodulin (Glucagon-37)
    • 2.3
      Relationship With Other Peptides
  • 3
    Structure of Preproglucagon Gene
  • 4
    Biosynthesis of Glucagon- and Gut Glucagon-Containing Peptides
  • 5
    Distribution of Oxyntomodulin and Glicentin
  • 6
    Biological Activities of Oxyntomodulin and Glicentin
    • 6.1
      Properties of Glucagon
    • 6.2
      Interaction of Glicentin and Oxyntomodulin With Glucagon Targets
    • 6.3
      Tissue Specificity of Oxyntomodulin
  • 7
    Circulating Forms
  • 8
    Possible Roles in Physiology and Pathology
  • 9
    New Perspective: Other Preproglucagon Fragments
    • 9.1
      Proglucagon 51–61 (Glucagon 19–29)
    • 9.2
      Proglucagon 51–69 (Oxyntomodulin 19–37)
  • 10
    Conclusions