Standard Article

Secretory Membranes and the Exocrine Storage Compartment

Handbook of Physiology, The Gastrointestinal System, Salivary, Gastric, Pancreatic, and Hepatobiliary Secretion

  1. Richard S. Cameron,
  2. Peter Arvan,
  3. J. David Castle

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp060307

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Cameron, R. S., Arvan, P. and Castle, J. D. 2011. Secretory Membranes and the Exocrine Storage Compartment. Comprehensive Physiology. 107–126.

Author Information

  1. Departments of Cell Biology and Internal Medicine, Yale University School of Medicine, New Haven, Connecticut

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Granule Formation and Storage
  • 2
    Granule Isolation and Preparation of Membrane Subfractions
    • 2.1
      Secretory Granules
    • 2.2
      Membrane Subfractions
  • 3
    Composition of Exocrine Granule Membranes
    • 3.1
      Membrane Lipids
    • 3.2
      Membrane Proteins
  • 4
    Storage Function and Biophysical Properties of Secretion Granules
    • 4.1
      Granule Packaging, Stability, and Osmotic Behavior
    • 4.2
      Ion Permeation of Granule Membranes
    • 4.3
      Intragranular pH and Buffering Capacity
    • 4.4
      Hydrogen-ATPase Activity
  • 5
    Interactions With Cytoplasmic Proteins
    • 5.1
      Possible Roles of Microtubules
    • 5.2
      Microfilamentous Networks and Secretory Organelle Interactions
    • 5.3
      Other Polypeptides Binding to Secretory Membranes
    • 5.4
      Stimulus-Enhanced Phosphorylation of Membrane and Associated Proteins
  • 6
    Exocytosis
  • 7
    Recycling, Turnover, and Sorting from Other Vesicular Traffic
    • 7.1
      Fate of Reinternalized Secretory Membrane
    • 7.2
      Secretory Membrane as a Plasmalemmal Protein Carrier
    • 7.3
      Secretory Membrane and Sorting Sites