Standard Article

Cell Biology of Hydrochloric Acid Secretion

Handbook of Physiology, The Gastrointestinal System, Salivary, Gastric, Pancreatic, and Hepatobiliary Secretion

  1. John G. Forte1,
  2. Andrew Soll2

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp060311

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Forte, J. G. and Soll, A. 2011. Cell Biology of Hydrochloric Acid Secretion. Comprehensive Physiology. 207–228.

Author Information

  1. 1

    Department of Physiology-Anatomy, University of California, and Medical and Research Services,, Berkeley, California

  2. 2

    Wadsworth Veterans Administration Hospital Center and University of California, Los Angeles, California

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Functional Morphology of The Oxyntic Cell
    • 1.1
      General Structure
    • 1.2
      Ultrastructure of Oxyntic Cells
    • 1.3
      Membrane Turnover and Recycling
    • 1.4
      Cytoskeleton of Oxyntic Cell
  • 2
    Receptors Regulating Oxyntic Cell Function
    • 2.1
      Techniques for Studying Gastric Glands and Cell Preparations
    • 2.2
      Studies of Receptor Specificity
    • 2.3
      Receptors on Nonoxyntic Cells
  • 3
    Cellular Basis of Hydrochloric Acid Secretion
    • 3.1
      H+-K+-ATPase: the Primary H+-Pump Enzyme
    • 3.2
      Membrane Changes Associated With Hydrochloric Acid Secretion
    • 3.3
      Hydrochloric Acid Transport at the Apical Cell Membrane
    • 3.4
      Transport at the Basolateral Membrane
    • 3.5
      Oxyntic Cell Transport Model
  • 4
    Cell-Activation Mechanisms
    • 4.1
      Oxyntic Cell Activation by Cyclic AMP
    • 4.2
      Prostaglandin Inhibition of Oxyntic Cell Function
    • 4.3
      Oxyntic Cell Activation by Calcium-Dependent Mechanisms