Standard Article

Physical Chemistry of Bile

Handbook of Physiology, The Gastrointestinal System, Salivary, Gastric, Pancreatic, and Hepatobiliary Secretion

  1. Donna J. Cabral,
  2. Donald M. Small

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp060331

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Cabral, D. J. and Small, D. M. 2011. Physical Chemistry of Bile. Comprehensive Physiology. 621–662.

Author Information

  1. Biophysics Institute, Housman Medical Research Center, Departments of Medicine and Biochemistry, Boston University School of Medicine, Boston, Massachusetts, Massachusetts, Boston

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Structural and Surface Properties of Bile Salts
    • 1.1
      Molecular Structure
    • 1.2
      Crystal Structure
    • 1.3
      Surface Chemistry
    • 1.4
      Hydrophobic-Hydrophilic Balance
  • 2
    Aqueous Solution Properties of Bile Salts
    • 2.1
      Solubility in Water
    • 2.2
      Solubility in Organic Solvents
    • 2.3
      Ionization Behavior
    • 2.4
      Aggregation Behavior
  • 3
    Bile Salt–Lecithin Interactions
    • 3.1
      Composition of Lecithins in Bile
    • 3.2
      Bile Salt–Phospholipid–Water Systems
  • 4
    Cholesterol
    • 4.1
      Solubility in Aqueous Media
    • 4.2
      Cholesterol-Bile Salt Interactions
    • 4.3
      Cholesterol-Phospholipid Interactions
    • 4.4
      Quaternary System: Bile Salt-Phospholipid-Cholesterol-Water
  • 5
    Bile
    • 5.1
      Normal Bile
    • 5.2
      Metastable Bile
    • 5.3
      Cholesterol Crystal Formation in Bile
    • 5.4
      Secretion of Bile from the Hepatocyte