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G Protein-Coupled Receptors and the G Protein Family

Handbook of Physiology, The Endocrine System, Cellular Endocrinology

  1. Alfredo Ulloa-Aguirre1,2,
  2. P. Michael Conn3,4

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp070106

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Ulloa-Aguirre, A. and Conn, P. M. 2011. G Protein-Coupled Receptors and the G Protein Family. Comprehensive Physiology. 87–124.

Author Information

  1. 1

    Instituto Nacional de la Nutrición “Salvador Zubirán”, Department of Reproductive Biology, Mexico City, D. F., Mexico

  2. 2

    Oregon Regional Primate Research Center, Divisions of Neuroscience and Reproductive Sciences, Beaverton, Oregon

  3. 3

    Oregon Regional Primate Research Center, Divisions of Neuroscience and Reproductive Sciences, Beaverton, Oregon

  4. 4

    Oregon Health Sciences University, Department of Physiology and Pharmacology, Portland, Oregon

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Structure of G Protein-Coupled Receptors
    • 1.1
      General Features
    • 1.2
      Ligand-Binding Domain
    • 1.3
      G Protein-Coupling Domain
  • 2
    The Heterotrimeric G-Protein Family
    • 2.1
      General Features
    • 2.2
      G Protein-Regulatory Cycle
    • 2.3
      Structural and Functional Relationships of Gα-Subunit
    • 2.4
      Gβγ Structure and Function
  • 3
    Regulatory Mechanisms
    • 3.1
      Mechanisms that Regulate Receptor Function
    • 3.2
      G Protein-Mediated Regulatory Mechanisms