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Mammalian Gs-Stimulated Adenylyl Cyclases

Handbook of Physiology, The Endocrine System, Cellular Endocrinology

  1. Gezhi Weng,
  2. Yibang Chen,
  3. Ravi Iyengar

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp070108

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Weng, G., Chen, Y. and Iyengar, R. 2011. Mammalian Gs-Stimulated Adenylyl Cyclases. Comprehensive Physiology. 165–176.

Author Information

  1. Mount Sinai School of Medicine of the City University of New York, Department of Pharmacology, New York, New York

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Cloning of Mammalian Isoforms
  • 2
    Tissue Distribution of Various Adenylyl Cyclases
  • 3
    Structure and Catalytic Site
  • 4
    Basal Activity
  • 5
    Regulation by Protein–Protein Interactions
    • 5.1
      Ca2+/Calmodulin
    • 5.2
      G Protein Subunits
  • 6
    Regulation by Small Molecules
    • 6.1
      P-Site Ligands
    • 6.2
      Forskolin
    • 6.3
      Ca2+
  • 7
    Regulation by Protein Kinases
    • 7.1
      Protein Kinase A
    • 7.2
      Protein Kinase C
    • 7.3
      Calmodulin-Kinase
    • 7.4
      Other Protein Kinases
  • 8
    Future Directions