Standard Article

Membrane Receptor–Linked Disease States

Handbook of Physiology, The Endocrine System, Cellular Endocrinology

  1. V. Nebes,
  2. J. Wall

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp070112

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Nebes, V. and Wall, J. 2011. Membrane Receptor–Linked Disease States. Comprehensive Physiology. 293–324.

Author Information

  1. Allegheny General Hospital, The Thyroid Eye Disease Research Laboratory, Department of Ophthalmology, Pittsburgh, Pennsylvania

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Genetic Disorders of Receptor and Effector Molecules
    • 1.1
      Types of Receptor
    • 1.2
      Clinical Disorders
    • 1.3
      C Proteins
    • 1.4
      Receptors and Oncogenes
    • 1.5
      Antibodies Against Receptors and Autoimmune Disorders
  • 2
    Seven-Transmembrane-Receptor/G Protein–Coupled Disorders
    • 2.1
      Thyroid-Stimulating Hormone Receptor/Toxic Thyroid Hyperplasia/Thyroid-Stimulating Hormone Resistance
    • 2.2
      Luteinizing Hormone Receptor/Precocious Puberty/ Leydig Cell Hypoplasia
    • 2.3
      Adrenocorticotropic Hormone Receptor/Familial Glucocorticoid Deficiency
    • 2.4
      Arginine Vasopressin/Nephrogenic Diabetes Insipidus
    • 2.5
      Rhodopsin/Retinifis Pigmentosa
    • 2.6
      Parathyroid Hormone/Parathyroid Hormone–Related Peptide Receptor/Jansen-Type Metaphyseal Chondrodysplasia
    • 2.7
      β3-Adrenergic Receptor/Obesity
    • 2.8
      Growth Hormone–Releasing Hormone Receptor
    • 2.9
      Somatostatin Receptor
  • 3
    Mutations of G Proteins
    • 3.1
      s Mutations/Albright Hereditary Osteodystrophy
  • 4
    Single-Transmembrane-Receptor–Coupled Diseases
    • 4.1
      Insulin Receptor/Leprechaunism/Rabson-Mendenhall Syndrome/Type A Insulin Resistance
    • 4.2
      Growth Hormone Receptor/Laron Dwarfism
    • 4.3
      Insulin-Like Growth Factor-1 Receptor
  • 5
    Four-Transmembrane-Segment Receptor Diseases
    • 5.1
      Gamma-Aminobutyric Acid and Serotonin Receptors
    • 5.2
      Acetylcholine Receptor/Slow-Channel Syndrome
    • 5.3
      Abnormal Recognition, Regulation, and Signaling Pathways
  • 6
    Receptor-Specific Cross-Over Disease
    • 6.1
      Hyperprolactinemia Syndrome
    • 6.2
      Trophoblastic Tumors/Human Chorionic Gonadotropin
    • 6.3
      Non-Islet Cell Neoplasms/Type II Insulin-Like Growth Factor
  • 7
    Oncogenic Receptor Defects
    • 7.1
      Thyroid-Stimulating Hormone Receptor/ Thyroid Adenomas
    • 7.2
      s Mutations/McCune-Albright Syndrome
    • 7.3
      Disorders of Ras and Ras-Like Proto-oncogenes
  • 8
    Antireceptor Antibodies and Autoimmune Disease
    • 8.1
      Effect of Antireceptor Antibodies
    • 8.2
      Thyroid-Stimulating Hormone Receptor Antibodies and Graves' Disease
    • 8.3
      Thyroid Growth–Stimulating Antibodies
    • 8.4
      Insulin Receptor Antibodies
    • 8.5
      β-Adrenergic Receptor Antibodies
    • 8.6
      Myasthenia Gravis
    • 8.7
      Other Receptor Antibodies