Standard Article

Apoptosis

Handbook of Physiology, The Endocrine System, Cellular Endocrinology

  1. Sheau Yu Hsu,
  2. Aaron J. W. Hsueh

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp070120

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Hsu, S. Y. and Hsueh, A. J. W. 2011. Apoptosis. Comprehensive Physiology. 559–588.

Author Information

  1. Division of Reproductive Biology, Department of Gynecology and Obstetrics, Stanford University Medical School, Stanford, California

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Apoptotic Cell Death Shows Conserved Morphological and Biochemical Changes
    • 1.1
      Nuclear Condensation and Ladder Pattern of DNA Fragmentation
    • 1.2
      Cytoplasmic Shrinkage and Plasma Membrane Blebbing
    • 1.3
      Nuclear and Cytoplasmic Alterations
    • 1.4
      Phagocytosis
  • 2
    Cellular Mechanisms of Apoptosis Conserved During Evolution: Nematode as a Genetic Model
  • 3
    Genes Regulating Apoptosis
    • 3.1
      The ced-9/bcl-2 Gene Family
    • 3.2
      The ced-3/caspase Gene Family
    • 3.3
      Death Domain-Containing Proteins
    • 3.4
      Other Apoptosis Regulatory Genes
  • 4
    Extracellular Signaling of Apoptosis
    • 4.1
      Apoptosis Induction Is Cell Type-Specific
    • 4.2
      The Mammalian Ovary Model
    • 4.3
      Fas-Ligand/Fas Antigen and Apoptosis
  • 5
    Conclusion