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Regulation of Gluconeogenesis in Liver

Handbook of Physiology, The Endocrine System, The Endocrine Pancreas and Regulation of Metabolism

  1. Louis Hue

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp070220

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Hue, L. 2011. Regulation of Gluconeogenesis in Liver. Comprehensive Physiology. 649–657.

Author Information

  1. Department of Biochemistry and Cellular Biology, University of louvain Medical School, and Christian de Duve Institute of Cellular Pathology, Brussels, Belgium

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Gluconeogenic Substrates
  • 2
    Organization of Glycolysis and Gluconeogenesis
    • 2.1
      Occurrence of Futile Cycles
    • 2.2
      Metabolic Crossroads
    • 2.3
      Analysis of Flux Control
  • 3
    Regulation and Role of the Three Cycles
    • 3.1
      The Glucose–Glucose-6-Phosphate Cycle
    • 3.2
      The Fructose-6-Phosphate-Fructose-1,6-Bisphosphate Cycle
    • 3.3
      The Pyruvate–Phosphoenolpyruvate Cycle
  • 4
    Integrated Control by Substrates and Hormones
    • 4.1
      Coordinated Control of Flux by Metabolites
    • 4.2
      Short-Term Control by Hormones
    • 4.3
      Long-Term Control by Hormones and Substrates
    • 4.4
      Control by End Products
    • 4.5
      Inhibitors of Gluconeogenesis
  • 5
    Conclusions