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Renal Actions of Vasopressin

Handbook of Physiology, The Endocrine System, Endocrine Regulation of Water and Electrolyte Balance

  1. Mark A. Knepper1,
  2. Heinz Valtin2,
  3. Jeff M. Sands3

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp070313

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Knepper, M. A., Valtin, H. and Sands, J. M. 2011. Renal Actions of Vasopressin. Comprehensive Physiology. 496–529.

Author Information

  1. 1

    Renal Mechanisms Section, Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland

  2. 2

    Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire

  3. 3

    Renal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Vasopressin and the Urinary Concentrating and Diluting Mechanism
    • 1.1
      General Features of the Urinary Concentration and Dilution Process
    • 1.2
      Mechanism of Tubule Fluid Dilution
    • 1.3
      Mechanism of Tubule Fluid Concentration
    • 1.4
      Countercurrent Multiplication
    • 1.5
      Role of Vasopressin in Urinary Concentration and Dilution
  • 2
    Vasopressin Receptors
    • 2.1
      V1a and V1b Receptor Subtypes
    • 2.2
      V2 Receptors
    • 2.3
      Renal Localization
  • 3
    Regulation of Aquaporin Water Channels by Vasopressin
    • 3.1
      Aquaporin Structure
    • 3.2
      Localization of Aquaporins in the Kidney
    • 3.3
      Short- and Long-Term Regulation of Water Permeability in the Collecting Duct
    • 3.4
      Short-Term Regulation of Aquaporin-2 by Vasopressin-Induced Trafficking
    • 3.5
      Long-Term Regulation of Water Transport Through Regulation of Aquaporin Protein Abundance
    • 3.6
      Role of Vasopressin in Pathophysiological Stales Associated with Abnormalities of Water Balance
  • 4
    The Vasopressin-Regulated Urea Transporter
    • 4.1
      Physiological Evidence for a Vasopressin-Regulated Urea Transporter
    • 4.2
      Molecular Cloning of Renal Urea Transporters
    • 4.3
      Short-Term Regulation
    • 4.4
      Long-Term Regulation
  • 5
    Regulation of Loop of Henle Function by Vasopressin
    • 5.1
      Thick Ascending Limb
    • 5.2
      Thin Ascending Limb
  • 6
    Regulation of Renal Hemodynamics by Vasopressin
    • 6.1
      Medullary Blood Flow
    • 6.2
      Glomerular Function