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Roles of Parathyroid Hormone and Parathyroid Hormone–Related Peptide in Calcium Metabolism and Bone Biology: Biological Actions and Receptors

Handbook of Physiology, The Endocrine System, Endocrine Regulation of Water and Electrolyte Balance

  1. Harald Jüppner,
  2. John T. Jr. Potts

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp070317

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Jüppner, H. and Jr. Potts, J. T. 2011. Roles of Parathyroid Hormone and Parathyroid Hormone–Related Peptide in Calcium Metabolism and Bone Biology: Biological Actions and Receptors. Comprehensive Physiology. 663–698.

Author Information

  1. Endocrine Unit, Departments of Medicine and Pediatrics, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Parathyroid Hormone
    • 1.1
      Chemistry
    • 1.2
      Peripheral Metabolism
    • 1.3
      Actions in Kidney and Bone
  • 2
    Parathyroid Hormone-Related Peptide
    • 2.1
      Chemistry: Role of the Amino-terminal Portion in Calcium Metabolism
    • 2.2
      Biological Role in Bone Development
  • 3
    Receptors That Mediate Analogous and Distinct Molecular Actions of Parathyroid Hormone and Parathyroid Hormone–Related Peptide
    • 3.1
      The Parathyroid Hormone/Parathyroid Hormone–Related Peptide Receptor
    • 3.2
      The Type 2 Parathyroid Hormone Receptor
    • 3.3
      Additional Receptors
    • 3.4
      Structure-Based Design of Analogues
  • 4
    Summary