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Regulation and Actions of Corticotropin-Releasing Hormone

Handbook of Physiology, The Endocrine System, Coping with the Environment: Neural and Endocrine Mechanisms

  1. Stacie C. Weninger1,
  2. Joseph A. Majzoub2

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp070406

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Weninger, S. C. and Majzoub, J. A. 2011. Regulation and Actions of Corticotropin-Releasing Hormone. Comprehensive Physiology. 103–124.

Author Information

  1. 1

    Division of Endocrinology, Children's Hospital and Program in Neuroscience, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts

  2. 2

    Division of Endocrinology, Children's Hospital, Harvard Medical School, Boston, Massachusetts

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Corticotropin-Releasing Hormone Expression
  • 2
    Corticotropin-Releasing Hormone Receptors
  • 3
    Corticotropin-Releasing Hormone-Binding Protein
  • 4
    Corticotropin-Releasing Hormone-Like Molecules
  • 5
    Regulation of Corticotropin-Releasing Hormone Expression
    • 5.1
      Corticotropin-Releasing Hormone Gene Structure
    • 5.2
      Intracellular Second Messengers That Regulate Corticotropin-Releasing Hormone Gene Expression
    • 5.3
      Extracellular Ligands That Regulate Corticotropin-Releasing Hormone Expression and Release
  • 6
    Regulation of the Hypothalamic-Pituitary-Adrenal Axis
    • 6.1
      Role of Corticotropin-Releasing Hormone in Stimulating Corticotropin Synthesis and Release
    • 6.2
      Other Corticotropin-Releasing Factors
    • 6.3
      Role of Corticotropin-Releasing Hormone in Circadian Rhythm Generation of the Hypothalamic-Pituitary-Adrenal Axis
    • 6.4
      Role of Corticotropin-Releasing Hormone in Fetal Development
  • 7
    Role of Corticotropin-Releasing Hormone in Responses to Physiological and Psychological Stressors
    • 7.1
      Acute Stressors
    • 7.2
      Chronic Stressors
  • 8
    Role of Corticotropin-Releasing Hormone in Regulating Other Neuroendocrine Functions
    • 8.1
      Behavior
    • 8.2
      Appetite
    • 8.3
      Reproduction
    • 8.4
      Autonomic Function
  • 9
    Conclusion