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Development of the Hypothalamic-Pituitary-Adrenal Axis and the Stress Response

Handbook of Physiology, The Endocrine System, Coping with the Environment: Neural and Endocrine Mechanisms

  1. Claire-Dominique Walker1,
  2. K.J.S. Anand2,
  3. PAUL M. Plotsky3

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp070412

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Walker, C.-D., Anand, K. and Plotsky, P. M. 2011. Development of the Hypothalamic-Pituitary-Adrenal Axis and the Stress Response. Comprehensive Physiology. 237–270.

Author Information

  1. 1

    Department of Psychiatry, McGill University, Douglas Hospital Research Center, Montreal, Quebec, Canada

  2. 2

    Department of Pediatrics, Arkansas Children's Hospital, University of Arkansas for Medical Sciences, Little Rock, Arkansas

  3. 3

    Stress Neurobiology Laboratory, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia

Publication History

  1. Published Online: 1 JAN 2011


The sections in this article are:

  • 1
    Ontogeny of the Hypothalamic-Pituitary-Adrenal Axis
    • 1.1
      Hypothalamic Paraventricular Nucleus
    • 1.2
      Pituitary Function
    • 1.3
      Adrenal Function
    • 1.4
      Glucocorticoid Feedback
    • 1.5
      Hypothalamic-Pituitary-Adrenal Function and Stress Responsiveness in Development
  • 2