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Development of Individual Differences in Behavioral and Endocrine Responses to Stress: Role of the Postnatal Environment

Handbook of Physiology, The Endocrine System, Coping with the Environment: Neural and Endocrine Mechanisms

  1. Christian Caldji1,
  2. Dong Liu1,
  3. Shakti Sharma1,
  4. Josie Diorio1,
  5. Darlene Francis1,
  6. Michael J. Meaney1,
  7. Paul M. Plotsky2

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp070413

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Caldji, C., Liu, D., Sharma, S., Diorio, J., Francis, D., Meaney, M. J. and Plotsky, P. M. 2011. Development of Individual Differences in Behavioral and Endocrine Responses to Stress: Role of the Postnatal Environment. Comprehensive Physiology. 271–292.

Author Information

  1. 1

    Developmental Neuroendocrinology Laboratory, Douglas Hospital Research Center and Departments of Psychiatry and of Neurology and Neurosurgery, McGill University, Montreal, Canada

  2. 2

    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Hypothalamic-Pituitary-Adrenal Stress Response
  • 2
    Environmental Regulation of Hypothalamic-Pituitary-Adrenal Development
    • 2.1
      Effects of Handling (or Infantile Stimulation)
    • 2.2
      Effects of Prolonged Periods of Maternal Separation
    • 2.3
      Effects of Neonatal Endotoxin Exposure
  • 3
    Summary of Early Environmental Effects
    • 3.1
      Effects of Handling on Chronic Responses to Stress
    • 3.2
      Acute Stress Responses in Handled and Nonhandled Rats: Revisited
  • 4
    Summary
  • 5
    Biological Significance
  • 6
    Early Environmental Effects: The Levine Maternal Mediation Hypothesis
    • 6.1
      Stability of Individual Differences in Maternal Behavior
    • 6.2
      Transmission of Individual Differences in Maternal Care to Offspring
    • 6.3
      Mode of Transmission: Genomic or Nongenomic?
  • 7
    Conclusions