Standard Article

The Regulation of Growth by Insulinlike Growth Factor II

Handbook of Physiology, The Endocrine System, Hormonal Control of Growth

  1. Robert A. Richman

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp070522

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Richman, R. A. 2011. The Regulation of Growth by Insulinlike Growth Factor II. Comprehensive Physiology. 701–736.

Author Information

  1. Department of Pediatrics, College of Medicine, State University of New York Health Science Center, Syracuse, New York

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Biochemistry and Physiology of Insulin-Like Growth Factor II
    • 1.1
      Structure of Insulin-Like Growth Factor II
    • 1.2
      Serum Levels of Insulin-Like Growth Factor II
    • 1.3
      Autocrine/Paracrine Effects of Insulin-Like Growth Factor II
    • 1.4
      Receptors for Insulin-Like Growth Factor II
    • 1.5
      Insulin-Like Growth Factor Receptors and Insulin-Like Growth Factor II Action
    • 1.6
      Insulin-Like Growth Factor Binding Proteins and Insulin-Like Growth Factor II Action
    • 1.7
      Levels of Insulin-Like Growth Factor Binding Proteins in the Fetus
  • 2
    Role of Insulin-Like Growth Factor II in Fetal Growth
    • 2.1
      Effects of Insulin-Like Growth Factor II on Specific Fetal Tissues and the Placenta
    • 2.2
      Hormonal Regulation of Insulin-Like Growth Factor II in the Fetus
    • 2.3
      Fasting, Placental Insufficiency, and Hypoxia in Fetal Growth Retardation
  • 3
    Regulation of Insulin-Like Growth Factor II Secretion by Growth Hormone During Postnatal Life
    • 3.1
      Neonatal Life
    • 3.2
      Childhood
  • 4
    Insulin-Like Growth Factor II Gene Expression
    • 4.1
      Humans
    • 4.2
      Rodents
    • 4.3
      Beckwith-Wiedemann Syndrome
    • 4.4
      Tumors
  • 5
    Conclusions