Standard Article

Functional Ultrastructure of the Proximal Tubule

Handbook of Physiology, Renal Physiology

  1. Arvid B. Maunsbach,
  2. Erik Ilsø Christensen

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp080102

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Maunsbach, A. B. and Christensen, E. I. 2011. Functional Ultrastructure of the Proximal Tubule. Comprehensive Physiology. 41–107.

Author Information

  1. Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Location of Proximal Tubule
  • 2
    Fixation of Proximal Tubule Cells for Electron Microscopy
  • 3
    Ultrastructure of the Mammalian Proximal Tubule Cell
    • 3.1
      General Cytology
    • 3.2
      Cell Shape
    • 3.3
      Segmentation of the Mammalian Proximal Tubule
    • 3.4
      Luminal Cell Surface
    • 3.5
      Basal and Lateral Cell Surface
    • 3.6
      Junctions
    • 3.7
      Nucleus
    • 3.8
      Mitochondria
    • 3.9
      Endoplasmic Reticulum
    • 3.10
      Golgi Apparatus
    • 3.11
      Vacuolar Apparatus (Lysosomes and Endocytic Vacuoles)
    • 3.12
      Peroxisomes
    • 3.13
      Cytoskeleton
    • 3.14
      Cytoplasmic Ground Substance and Inclusions
  • 4
    Structure of Proximal Tubule Cells in Submammalian Species
    • 4.1
      Birds
    • 4.2
      Reptiles
    • 4.3
      Amphibians
    • 4.4
      Fishes
  • 5
    Ultrastructure of Experimentally Perfused Tubules
  • 6
    Quantitative Ultrastructure of Proximal Tubules
  • 7
    Transepithelial Transport Routes
    • 7.1
      The Transcellular Route
    • 7.2
      The Paracellular Route
  • 8
    Functions of the Vacuolar Apparatus
    • 8.1
      Protein Absorption by the Proximal Tubule Cells
    • 8.2
      Transtubular Transport of Proteins
    • 8.3
      Basolateral Binding and Uptake of Proteins
    • 8.4
      Endocytosis of Nonproteins
    • 8.5
      Autophogocytosis
    • 8.6
      Lysosomal Accumulation of Metals and Other Substances