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Renal Handling of Urea

Handbook of Physiology, Renal Physiology

  1. Donald J. Marsh1,
  2. Mark A. Knepper2

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp080229

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Marsh, D. J. and Knepper, M. A. 2011. Renal Handling of Urea. Comprehensive Physiology. 1317–1347.

Author Information

  1. 1

    Department of Physiology and Biophysics, University of Southern California School of Medicine, Los Angeles, California

  2. 2

    Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Urea Synthesis
  • 2
    Role of Urea in Systemic Metabolism
    • 2.1
      Role of Urea in Systemic Nitrogen Balance
    • 2.2
      Role of Urea in Systemic Acid-Base Balance
    • 2.3
      Regulation of Urea Production and Excretion
  • 3
    Effects of Urea on Cellular Function: Role of Methylamines
  • 4
    Membrane Transport of Urea
    • 4.1
      Lipid Bilayers
    • 4.2
      Erythrocytes and Other Nonepithelial Cells
    • 4.3
      Nonrenal Epithelia
  • 5
    Urea Transport in the Kidney
    • 5.1
      Introduction
    • 5.2
      Individual Tubule Segments
  • 6
    Role of Urea in the Urinary Concentrating Mechanism
  • 7
    Questions Remaining