Standard Article

Regional Deposition of Particles in the Human Respiratory Tract

Handbook of Physiology, Reactions to Environmental Agents

  1. Morton Lippmann

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp090114

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Lippmann, M. 2011. Regional Deposition of Particles in the Human Respiratory Tract. Comprehensive Physiology. 213–232.

Author Information

  1. Institute of Environmental Medicine, New York University Medical Center, New York, New York

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Clearance Zones in the Respiratory Tract
    • 1.1
      Anterior Nares
    • 1.2
      Ciliated Nasal Passages
    • 1.3
      Nasopharynx, Oral Passages, and Larynx
    • 1.4
      Tracheobronchial Tree
    • 1.5
      Alevolar Zone
  • 2
    Factors Affecting Regional Particle Deposition
    • 2.1
      Deposition Mechanisms
    • 2.2
      Aerosol Factors
    • 2.3
      Respiratory and Flow Factors
    • 2.4
      Anatomical Factors
    • 2.5
      Physiological Factors
    • 2.6
      Environmental Factors
    • 2.7
      Effects of Pollutant Gases and Aerosols
    • 2.8
      Effects of Chronic Lung Disease
  • 3
    Techniques for Measuring Particle Deposition
    • 3.1
      Comparison of Particle Contents in Inhaled and Exhaled Air
    • 3.2
      External in vivo Measurement of γ-Labeled Particle Retention
    • 3.3
      Sacrifice and Dissection by Regions in Experimental Animals
    • 3.4
      Deposition in Model Systems and Excised Lungs
  • 4
    Experimental Regional Deposition Data
    • 4.1
      Deposition in Human Beings
    • 4.2
      Deposition in Experimental Animals
  • 5
    Predictive Deposition Models
  • 6
    Deposition of Ambient Atmospheric Aerosol