Standard Article

Metabolism of Foreign Substances in the Gastrointestinal Tract

Handbook of Physiology, Reactions to Environmental Agents

  1. Kaarlo Hartiala

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp090123

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Hartiala, K. 2011. Metabolism of Foreign Substances in the Gastrointestinal Tract. Comprehensive Physiology. 375–388.

Author Information

  1. Department of Physiology, University of Turku, Turku, Finland

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Foreign Substance Metabolism by the Intestinal Mucosa
    • 1.1
      Nonsynthetic Reactions
    • 1.2
      Synthetic Reactions
  • 2
    Multiplicity of Biotransformation Reactions
  • 3
    Species and Strain Differences
  • 4
    Fetal Development and Phylogenetic Aspects
  • 5
    Biotransformation by Intestinal Microorganisms
  • 6
    Adaptation of Xenobiotic Metabolism in the Gastrointestinal Tract
    • 6.1
      Endogenous Compounds in Regulation of Drug Metabolism
    • 6.2
      Enhancement of Biotransformation by Exogenous Compounds
    • 6.3
      Effect of Luminal Contents
    • 6.4
      Interaction of Intestinal Microflora and Mucosal Functions
  • 7
    Concluding Remarks