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Hepatic and Extrahepatic Mixed-Function Oxidases

Handbook of Physiology, Reactions to Environmental Agents

  1. John R. Bend,
  2. Gary E. R. Hook

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp090126

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Bend, J. R. and Hook, G. E. R. 2011. Hepatic and Extrahepatic Mixed-Function Oxidases. Comprehensive Physiology. 419–440.

Author Information

  1. Pharmacology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Types of Mixed-Function Oxidase Reactions
  • 2
    Characteristics of Microsomal Electron Transport Chain
    • 2.1
      Cytochrome P-450
    • 2.2
      Substrate-Induced Difference Spectra
    • 2.3
      Cytochrome P-450 Reductase
    • 2.4
      Reconstituted Microsomal Enzyme Systems
  • 3
    Extrahepatic Mixed-Function Oxidase Activity
    • 3.1
      Lung
    • 3.2
      Kidney
    • 3.3
      Gastrointestinal Tract
    • 3.4
      Placenta
    • 3.5
      Skin
    • 3.6
      Adrenals
    • 3.7
      Miscellaneous Organs
  • 4
    Hepatic and Extrahepatic Mixed-Function Oxidase Activity in Perinatal Period
  • 5
    Induction of Hepatic and Extrahepatic Mixed-Function Oxidase Activity
  • 6
    Hormonal Regulation of Hepatic and Extrahepatic Mixed-Function Oxidases
  • 7
    Mixed-Function Oxidase Activity in Human Beings
    • 7.1
      Drug Interactions
  • 8
    Conclusion