Standard Article

Action of Environmental Agents on Nucleic Acids and Their Metabolism

Handbook of Physiology, Reactions to Environmental Agents

  1. Walter Troll1,
  2. Robert Shapiro2

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp090140

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Troll, W. and Shapiro, R. 2011. Action of Environmental Agents on Nucleic Acids and Their Metabolism. Comprehensive Physiology. 615–624.

Author Information

  1. 1

    Department of Environmental Medicine, New York University Medical Center, New York, New York

  2. 2

    Department of Chemistry, New York University, Washington Square, New York, New York

Publication History

  1. Published Online: 1 JAN 2011


The sections in this article are:

  • 1
    Chemical Reactions That Modify Nucleic Acids
    • 1.1
      Noncovalent Interactions
    • 1.2
      Covalent Interactions
    • 1.3
      Chemical Consequences of Modification
  • 2
    Biological Consequences of Modification
    • 2.1
      Mutagenesis: Carcinogenesis
    • 2.2
      DNA Repair Synthesis
  • 3
    Examples of Environmental Chemicals that React with Nucleic Acids
    • 3.1
      Chemicals Requiring No Prior Activation
    • 3.2
      Chemicals Requiring Prior Activation