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Pharmacological Investigations of Excitation-Contraction Coupling

Handbook of Physiology, Skeletal Muscle

  1. Carlo Caputo

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp100114

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Caputo, C. 2011. Pharmacological Investigations of Excitation-Contraction Coupling. Comprehensive Physiology. 381–415.

Author Information

  1. Centro de Biofísica y Bioqúimica, Institute Venezolano de Investigaciones Científicas, Caracas, Venezuela

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Excitation-Contraction Coupling Phenomena
    • 1.1
      Active State
    • 1.2
      Regulation of Calcium Release
    • 1.3
      Mechanically Effective Period
    • 1.4
      Contractile Threshold
    • 1.5
      Potassium Contracture
    • 1.6
      Tension Development With Voltage Clamp
    • 1.7
      Calcium Indicators
    • 1.8
      Calcium-Induced Calcium Release
    • 1.9
      Depolarization-Induced Calcium Release
    • 1.10
      Membrane Potential Changes at SR Level
  • 2
    Pharmacological and Experimental Modifications of ECC
    • 2.1
      Effect of Extracellular Calcium
    • 2.2
      Effect of Hypertonic Solutions
    • 2.3
      Transverse-Tubule Disrupture (Glycerol Treatment)
    • 2.4
      Effects of Anions
    • 2.5
      Effects of Cations
    • 2.6
      Drugs That Activate or Potentiate Contraction
    • 2.7
      Drugs That Depress Contraction
    • 2.8
      Other Treatment