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Control of Blood Flow to Cardiac and Skeletal Muscle During Exercise

Handbook of Physiology, Exercise: Regulation and Integration of Multiple Systems

  1. M. Harold Laughlin1,
  2. Ronald J. Korthuis2,
  3. Dirk J. Duncker3,
  4. Robert J. Bache4

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp120116

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Laughlin, M. H., Korthuis, R. J., Duncker, D. J. and Bache, R. J. 2011. Control of Blood Flow to Cardiac and Skeletal Muscle During Exercise. Comprehensive Physiology. 705–769.

Author Information

  1. 1

    Department of Veterinary Biomedical Sciences, University of Missouri, Columbia, Missouri

  2. 2

    Department of Physiology and Biophysics, Louisiana State University Medical Center, Shreveport, Louisiana

  3. 3

    Experimental Cardiology, Thoraxcenter, Erasmus University Rotterdam, Rotterdam, The Netherlands

  4. 4

    Department of Medicine, Cardiovascular Division, University of Minnesota Medical School, Minneapolis, Minnesota

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Hemodynamics and Control of Blood Flow
    • 1.1
      Determinants of Vascular Resistance
    • 1.2
      Central Vascular Control Mechanisms
    • 1.3
      Local Vascular Control Mechanisms
  • 2
    Coronary Vascular Response to Exercise
    • 2.1
      Effect of Exercise on Left Ventricular Blood Flow
    • 2.2
      Right Ventricular Blood Flow during Exercise
    • 2.3
      Mechanisms Of Coronary Vasodilation during Exercise
    • 2.4
      Autonomic Nervous System Influences
    • 2.5
      Extravascular Determinants of Coronary Blood Flow
    • 2.6
      Epicardial Coronary Arteries
  • 3
    Effects of Physical Conditioning on the Coronary Circulation
    • 3.1
      Structural Adaptations
    • 3.2
      Adaptations of Neurohumoral Control
    • 3.3
      Local Coronary Vascular Control
    • 3.4
      Integrated Coronary Vascular Adaptations
    • 3.5
      Extravascular Determinants of Coronary Blood Flow
  • 4
    Skeletal Muscle Blood Flow During Exercise
    • 4.1
      Skeletal Muscle Blood Flow during Isometric Contraction
    • 4.2
      Skeletal Muscle Exercise Hyperemia
    • 4.3
      Regional Distribution of Skeletal Muscle Blood Flow
    • 4.4
      Mechanisms of Exercise Hyperemia
    • 4.5
      Regulation of Transcapillary Fluid and Solute Exchange in Skeletal Muscle
    • 4.6
      Regulation of Tissue Oxygenation in Exercising Skeletal Muscles
    • 4.7
      Determinants of Skeletal Muscle Arteriovenous Oxygen Difference
  • 5
    Effects of Physical Conditioning on Skeletal Muscle Vascular Beds
    • 5.1
      Skeletal Muscle Blood Flow Capacity
    • 5.2
      Skeletal Muscle Capillary Diffusion Capacity
    • 5.3
      Structural Vascular Adaptation
    • 5.4
      Adaptations of Vascular Control
  • 6
    Conclusion